Identifying all irreducible conserved metabolite pools in genome-scale metabolic networks: a general method and the case of Escherichia coli
نویسندگان
چکیده
A. De Martino,1, 2, 3, ∗ D. De Martino,3, ∗ R. Mulet,4, ∗ and A. Pagnani5, 6, ∗ IPCF-CNR, Unità di Roma-Sapienza, Roma (Italy) Dipartimento di Fisica, Sapienza Università di Roma, p.le A. Moro 2, 00185 Roma (Italy) Center for Life Nano Science@Sapienza, Istituto Italiano di Tecnologia, Viale Regina Elena 291, 00161 Roma (Italy) Henri-Poincaré-Group of Complex Systems and Department of Theoretical Physics, Physics Faculty, University of Havana, CP 10400 La Habana (Cuba) DISAT and Centre for Computational Sciences, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino (Italy) Human Genetics Foundation, Via Nizza 52, 10126 Torino (Italy)
منابع مشابه
Elucidation and structural analysis of conserved pools for genome-scale metabolic reconstructions.
In this article, we introduce metabolite concentration coupling analysis (MCCA) to study conservation relationships for metabolite concentrations in genome-scale metabolic networks. The analysis allows the global identification of subsets of metabolites whose concentrations are always coupled within common conserved pools. Also, the minimal conserved pool identification (MCPI) procedure is deve...
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